cacoready kit vitro evaluation drug permeability caco-2 monolayers (ADMEcell Inc)
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Cacoready Kit Vitro Evaluation Drug Permeability Caco 2 Monolayers, supplied by ADMEcell Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cacoready+kit+vitro+evaluation+drug+permeability+caco-2+monolayers/cacoready+kit+vitro+evaluation+drug+permeability+caco+2+monolayers/pmc03612132-179-11-16
Average 90 stars, based on 1 article reviews
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1) Product Images from "Application of activated nucleoside analogs for the treatment of drug-resistant tumors by oral delivery of nanogel-drug conjugates"
Article Title: Application of activated nucleoside analogs for the treatment of drug-resistant tumors by oral delivery of nanogel-drug conjugates
Journal: Journal of controlled release : official journal of the Controlled Release Society
doi: 10.1016/j.jconrel.2013.01.020
Figure Legend Snippet: (A) Gastrointestinal (GI) transfer efficacy of nanogel-drug conjugates, empty nanogels and free drugs in Caco-2 cell monolayers. (A) Percentage of drug transfer across the Caco-2 cell monolayer: (a) empty nanogel without drug, (b–d) nanogel-drug conjugates, and (e–f) free nucleoside analogs, Floxuridine and Gemcitabine (60–240 min incubation at 37°C). Data represents means ± SEM (n=3). (B) Permeability coefficients of nanogel-drug conjugates and free drugs calculated from the transfer data. Papp were compared for each formulation to determine their GI transport efficacy.
Techniques Used: Incubation, Permeability
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